Mortal Kombat Mythologies: Sub-Zero is a game from the Mortal Kombat fighting game series. It featured the original Sub-Zero in an adventure to defeat Quan Chi from retrieving an amulet that would free the fallen Elder God Shinnok.

Although released five years after the first Mortal Kombat game, the storyline in Mortal Kombat Mythologies: Sub-Zero dates back furthest chronologically, even before the first game. This was done to further expand elements on the existing storyline, especially concerning Quan Chi, Sub-Zero, Scorpion, Shinnok, and the Lin Kuei.

Thousands of years ago, Shinnok existed as an Elder God. The Elder Gods are the true rulers of all realms. They watch as worlds are created and destroyed and govern the realms with untold eons of wisdom. Shinnok, however, gave in to greed and illusions of false power through the new realm of Earth. If he could have that realm to himself, he would have power unmatched. To accomplish his goal, he first would have to face the god of thunder known as Raiden, who was appointed as Earth's guardian by the Elder Gods themselves. Their battle for the realm of Earth was fierce; causing the planet's near destruction and plunging it into centuries of darkness.